2017年度中医内科学重点实验室发表学术论文共计77篇，其中SCI收录合计33篇，第一作者或通讯作者单位23篇，影响因子合计124.732，单篇最高影响因子17.202；中文期刊发表论文合计44篇，核心期刊收录44篇。

英文文章

1.心血管病方向

[1] Wu AM#, Lou LX, Zhai JY, Zhang DM, Chai LM, Nie B, Zhu HY, Gao YH,Shang HC, Zhao MJ*. miRNA Expression Profile and Effect of Wenxin Granule inRats with Ligation-Induced Myocardial Infarction[J]. Int J Genomics. 2017. （SCI收录，IF2.402）...............................................................................................................1

[2] Wu AM#, Zhao MJ, Lou LX, Zhai JY, Zhang DM, Zhu HY, Gao YH, ShangHC, Chai LM*. Effect of WenxinGranules on Gap Junction and MiR-1 in Rats with Myocardial Infarction[J].Biomed Res Int. 2017.（SCI收录，IF2.476）...........................................................................................................................2

[3]  Shen ST, Jiang HM, BeiYH, Zhang JL, Zhang HF, Zhu HS, Zhang CL, YaoWM, Wei C, Shang HC*, Li XL*.Qiliqiangxin Attenuates Adverse Cardiac Remodeling after Myocardial Infarctionin Ovariectomized Mice via Activation of PPAR gamma. Cell Physiol Biochem. 2017;42(3): 876-888. （SCI收录，IF5.104）...........................................................................................................................3

[4] Li J, Li Y, Zhang Y, Hu D, GaoYH, Shang HC*, Xing YW*. TheInhibitory Effect of WenxinKeli on H9C2 Cardiomyocytes Hypertrophy Induced byAngiotensin II through Regulating Autophagy Activity. Hindawi OxidativeMedicine and Cellular Longevity Volume.11.2017. （SCI收录，IF4.593）..........................................................................................................................4

[5] Yang XY, Li Y, Ren XM, XiongXJ, Wu LJ, Li J, Wang J, Gao YH, ShangHC*, Xing YW*. Effects of exercise-based cardiac rehabilitation in patientsafter percutaneous coronary intervention: A meta-analysis of randomizedcontrolled trials[J]. Sci Rep. 2017;7（SCI收录，IF4.259）...........................................................................................................................5

[6] Li M, Xu X, Yang XY, Kwong JSW,Shang HC*. The cardioprotective andantiarrhythmic effects of Nardostachyschinensis in animal and cell experiments [J]. BMCComplement Altern Med. 2017;17. （SCI收录，IF2.288）....... ........................6

[7] Yang XY, Chen Y, Li YD, Ren XM,Xing YW*, Shang HC*. Effects ofWenxin Keli on Cardiac Hypertrophy and Arrhythmia via Regulation of theCalcium/Calmodulin Dependent Kinase II Signaling Pathway[J]. Biomed Res Int. 2017. （SCI收录，IF2.476）....... ............................................................................7

[8] Li M, Qiu RJ, Tian GH, ZhangXY, Li CY, Chen SQ, Zhang Q, Shang HC*.Wenxin Keli for Ventricular premature complexes with Heart failure: ASystematic Review and Meta-Analysis of Randomized Clinical Trials[J]. Complement Ther Med.2017;33:85-93.（SCI收录，IF 2.013）....................................................................8

[9] Wang H, Liu CX, Zhai JB, Shang HC*. NiuhuangJiangya Preparation(a traditional Chinese patent medicine) for essential hypertension: Asystematic review, [J]. Complement Ther Med. 2017;31:90-99. （SCI收录，IF2.013）.. ....................9

[10]Li J, Gao YH, Ren XM, Li YD, WuLJ, Yang XY, Wang J, Shang HC, XiongXJ*, Xing YW*. The Role of Biologically Active Ingredients from Chinese HerbalMedicines in the Regulation of Autophagy in Treating Cardiovascular Diseasesand Other Chronic Diseases[J]. Curr PharmDesign. 2017;23(7):1060-1069.（SCI收录，IF2.611）.. ..................................................................................................................10

[11] Li YD, Barajas-Martinez H, LiB, Gao YH, Zhang ZP, Shang HC, Xing YW*, Hu D*. ComparativeEffectiveness of Acupuncture and Antiarrhythmic Drugs for the Prevention ofCardiac Arrhythmias: A Systematic Review and Meta-analysis of RandomizedControlled Trials[J]. Front Physiol. 2017;8.（SCI收录，IF 4.134）.........................................................................................................................11

2.脑血管病方向

[12] Wu LJ, Li YD, Wang XF, Ren XM, Zhu HY, Sun YK, Xing YW, Zhu LQ, Gao YH*, Shang HC*. A Systematic Review and Meta-Analysis on the Treatmentof Cerebral Hemorrhage with NaoXueShu Oral Liquid.Biomed Res Int.2017;2017:8542576. （SCI收录，IF 3.568）.............................................................12

[13]Li J,Hu D,Song X,Han T,Gao Y*,Xing Y*.The Role ofBiologically Active Ingredients from Natural Drug Treatments for Arrhythmias inDifferent Mechanisms. Biomed Res Int. 2017;2017:4615727. doi:10.1155/2017/4615727（SCI收录，IF2.476）......................................................................................................13

[14]Shi X#, Yu W, Liu L, Liu W, Zhang X, Yang T, Chai L, Lou L, Gao Y, ZhuL*.

Panax notoginseng saponinsadministration  modulates pro-/anti-inflammatory

factor expression andimproves neurologic outcome following permanent MCAO in rats.Metab Brain Dis.2017;32(1):221-233. （SCI收录，IF2.29）........................................................................................................................14

[15]Xiaomeng Ren, Yanda Li, Xinyu Yang, Jie Li, Huilong Li, ZhengzhongYuan,Yikun Sun, Hongcai Shang, Yanwei Xing* and Yonghong Gao*. The Effects of Tai Chi Training in Patients withHeart Failure: A Systematic Review and Meta-Analysis. FrontPhysio.2017, 8: 989（SCI收录，IF4.112）..............................15

3.肾脏病、内分泌、风湿免疫方向

[16] Wang H, Guo LP*, Shang HC*, Ren M, Wang XM, Wang DH, Chen JZ, Li SL, Chen LM, WangY, Liu Z, Zhai JB, Song YZ, Cao HB, Zhang JH, Liu CX, Sun X, Huo D, Mu W, ZhangL, Zheng WK, Yan XY, Yao C. JinqiJiangtang tablets for prediabetes: Arandomized, double-blind and placebo-controlled clinical trial[J]. Sci Rep. 2017;7（SCI收录，IF4.259）..........................................................................16

[17]Xing DM, Zhang JH, Zhu MJ*, ZhaoY, Shang HC. Adherence reporting in clinical trials of type 2 DiabetesMetellius in the field of Traditional Chinese Medicine[J]. J Tradit Chin Med. 2017;37(1):140-142. （SCI收录，IF0.991）..........17

[18]Jingwei Zhou#, Xue Li, Peiying Deng, Yi Wei, Juan Liu, Meng Chen, YameiXu,Dongmei Zhang, Lingqun Zhu, Lixia Lou, Bin Dong, Qiushuo Jin, and Limin Chai*. Chinese Herbal Formula,Modified Danggui Buxue Tang,Attenuates Apoptosis of Hematopoietic Stem Cells inImmune-Mediated Aplastic Anemia Mouse Model. Journal of Immunology Research.2017, 9786972.（SCI收录，IF3.276）......................................................................................................................18

[19]heng W#, Zhang YS#, Li YQ, Wu XN, Chai LM, Yue LF, Juan-Liu, Ding J, Li XR,ChenM, Shang JW*. Effect of yishenjianpi recipe on semen quality andspermmitochondria in mice with oligoasthenozoospermia induced by Tripterygiumglycosides. Afr J Tradit Complement Altern Med. 2017;14(4):87-95. （SCI收录，IF0.5）..........................................................................................................................19

[20]Li JY#, Jia YS#, Chai LM, Mu XH, Ma S, Xu L*, Wei X. Effects of Chineseherbal formula Erxian decoction for treating osteoporosis: a systematic review.Clin Interv Aging. 2017;12:45-53.（SCI收录，IF2.58）.................................................20

[21]Deng P#, Li X, Wei Y, Liu J, Chen M, Xu Y, Dong B, Zhu L, Chai L*. The herbal decoction modifiedDanggui Buxue Tang attenuates immune-mediated bone marrow failure by regulatingthe differentiation of T lymphocytes in an immune-induce daplastic anemia mousemodel. PLoS One. 2017;12(7):e0180417. （SCI收录，IF2.805）................................................................................................21

[22]Li J#, Wei Y, Li X, Zhu D, Nie B,Zhou J, Lou L, Dong B, Wu A, Che Y, Chen M,Zhu L, Mu M, Chai L*. Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiationof lymphocytes and production of pro-inflammatory cytokines incollagen-inducedarthritis mice. BMC Complement Altern Med. 2017;17(1):12. （SCI收录，IF2.288）..............................................................................................22

[23]Yu Ning Liu#, Jingwei Zhou, Tingting Li, Jing Wu,2Shu Hua Xie, Hua-feng Liu,Zhangsuo Liu,Tae Sun Park, Yaoxian Wang*, and WeiJing Liu*.Sulodexide Protects Renal Tubular Epith elial Cells from Oxidative Stress- Induced Injury via Upregulating Klotho Expression at an Early Stage of Diabetic Kidney Disease. Hindawi journal ofDiabetes Research Volume 2017.（SCI收录，IF2.013）........23

[24]Jie Lv#,1 Zhen Wang,1 Ying Wang,1 Weiwei Sun,1 Jingwei Zhou,1 Mengdi Wang,Wei Jing Liu*,andYaoxian Wang*.Renoprotective Effect of theShen - Yan - F ang - Shuai Formula by Inhibiting TNF-α/NF-κB Signaling Pathwayin Diabeti c Rats. Journal of Diabetes Research. Volume 2017. （SCI收录，IF2.717）.........................24

[25]Wei Jing Liu#, Zhi-hang Li, Xiao-cui Chen, Xiao-lu Zhao, Zhen Zhong, ChenYang, Hongluan Wu, Ning An, Wei-yan Li & Hua-feng Liu. Blockage of the lysosome-dependent autophagic pathway contributesto complement membrane attack complex-induced podocyte injury in idiopathic membranousnephropathy. Received: SCIENTIFIC REPORTS. 4 October 2016Accepted: 5 July 2017（SCI收录，IF4.259）.......................................................................................................................25

4.临床评价方向

[26]Chen YL*, Yang KH, Marusic A, Qaseem A, Meerpohl JJ, Flottorp S, Akl EA,Schunemann HJ, Chan ESY, Falck-Ytter Y, Ahmed F, Barber S, Chen CF, Zhang MM,Xu B, Tian JH, Song FJ, Shang HC,Tang K, Wang Q, Norris SL, Practice RRI. A Reporting Tool for Practice Guidelinesin Health Care: The RIGHT Statement. Z Evid Fortbild QualGesundhwes. 2017 Nov;127-128:3-10（SCI收录，IF17.202）......26

[27] Cheng CW, Wu TX, Shang HC,Li YP, Altman DG, Moher D, Bian ZX*, Grp CF. CONSORT Extension for ChineseHerbal Medicine Formulas 2017: Recommendations, Explanation, and Elaboration.Ann Intern Med. 2017, 112-121.（SCI收录，IF17.202）................................................................................................27

5.中药药理及作用机制方向

[28]Ni JN, Zhang XK, Yang YC, Liu XM, Wei MQ, Li T, Wang PW, Tian JZ, Wang YY*.Effect of GAPT extract on expression oftau protein and its phosphorylation related enzymes in hippocampal neurons ofAPPV717I transgenic mice. Chin J Integr Med .2017, 605-610.（SCI收录，IF1.116)...............................................................28

[29]D Zhao, Feng Feng, Fei Yuan, Jin Su, Yan Cheng, Hanqiu Wu, Kun Song, Bo Nie, Lian Yu, FengZhang*.Simultaneous determination of 13 carbohydrates using high-performance anion-exchangechromatography coupled with pulsed amperometric detection and massspectrometry. J Sep Sci. 2017;40(8):1843-1854. （SCI收录，IF2.741 ）...........................................................................................29

[30]Wang P#, Su C, Feng H, Chen X, Dong Y,Rao Y, Ren Y, Yang J, Shi J, Tian J*, Jiang S. Curcumin regulates insulinpathways and glucose metabolism in the brains of APPswe/PS1dE9 mice[J].Int JImmunopathol Pharmacol. 2017;30(1):25-43.（SCI收录，IF2.347 ）........................................................................................................30

[31] Zhang WK, Gu HW, Li XJ, Li YS*, Tang HB*, Tian GH, Shang HC*. The dark side of "the force"- lipidnanoparticles enhance the oncogenesis of diethylnitrosamine and result in livercancer in mice. Nanomedicine. 2017.（SCI收录，IF5.72）.............................................................................................................31

[32] Yang XY, Li Y, Li YD, Ren XM, Zhang XY, Hu D, Gao YH, Xing YW*, Shang HC*.Oxidative Stress-Mediated Atherosclerosis: Mechanisms and Therapies. FrontPhysiol. 2017.（SCI收录，IF4.134）............................................................32

[33] Li XJ, Mu YM, Qin QF, Zeng ZX, Li YS, Zhang WK, Tang HB*, Tian GH, Shang HC*. Chronic high-dosage fish oilexacerbates gut-liver axis injury in alcoholic steatohepatitis in mice: theroles of endotoxin and IL-4 in Kupffer cell polarization imbalance. Toxicologicalresearch.2017.（SCI收录，IF1.969）......................................................................................................................33

备注：#：共同第一作者；*：通讯作者

中文文章

1.心血管病方向

[1] 苏都娜,策力木格,侯彦宏,图雅*,聂波. 蒙药复方五味清浊散研究进展[J]. 现代中西医结合杂志, 2017,26(13):1479-1482. ..................................................34

[2] 郑婧,张贵君*,孙湛,聂波,渠磊,武亚楠,郭怡祯. 木耳超微粉降血脂作用研究[J]. 西部中医药, 2017,30(04):20-22. ...... ....................................................35

[3]聂波，徐冰，陈立新，赵明镜，吴爱明，娄利霞，郑思新，吴圣贤*，四妙勇安汤活性部位灌胃给药的急性毒性实验研究，河北中医，2017,39(01):100-103. .............................................................................................36

[4] 侯彦宏,沈晓旭,宫媛媛,赵明镜,吴爱明,娄利霞,金秋硕,吴圣贤,聂波*. 四妙勇安汤活性部位对一氧化氮合成酶抑制剂诱导的高血压大鼠血管重构的作用[J].中国实验方剂学杂志,2017,23(04):112-117.................................................37

[5]李承羽,张晓雨,唐潇旖,李敏,杨欣宇,商洪才*. 瓜蒌皮注射液联合常规用药治疗心绞痛的系统评价[J]. 中国循证医学杂志,2017,17(09):1072-1078.....38

[6]路晶晶,雷翔,商洪才*.丹蒌片治疗痰瘀互阻型稳定型心绞痛的系统评价[J]. 中西医结合心脑血管病杂志,2017,15(10):1198-1202........................................39

[7]吴爱明,赵明镜,张冬梅,朱海燕,柴立民,聂波,金秋硕,赵一舟,王硕仁,娄利霞*.气血宁对心肌梗死大鼠心脏保护作用机制研究[J]. 北京中医药,2017(05):405-409+481. .....................................................................................40

[8]董竞方,赵明镜*. 超声心动图对成人右心室功能评估的临床意义[J]. 中国医药导报,2017,14(11):35-38. ...............................................................................41

[9]韩安邦,张健,路迎冬,赵明镜,赵一舟,何姚姚,崔向宁*. 芪苈强心胶囊对心肌梗死大鼠心肌纤维化及TGF-β_1/Smad3信号通路的影响[J]. 北京中医药大学学报,2017,40(01):41-47...................................................................................42

[10]文堃,祁轶斐,陈萌,娄利霞,董玢,赵一舟,金秋硕,任学娇,朱珂,张冬梅*. 活血益气方及其拆方对缺氧人脐静脉内皮细胞增殖和凋亡的影响[J].中医杂志, 2017,58(09):777-781. ............................................................................................43

2.脑血管病方向

[11]常佩芬,唐蓓蕾,郭宁,赵红霞,赵勇,高永红,朱海燕.清开灵注射液对老年痴呆小鼠血液、脑组织Aβ含量及神经递质的影响[J].中国中医基础医学杂志,2017,23(11):1552-1553+1572.........................................................................44

[12]李亚，石凤芹，朱陵群，董青，侯丽等。新加良附方抑制人胃癌细胞增殖的分子机制.世界中医药，2017,12（9）2134-2138. .............................................45

3.临床评价方向

[13]张晓雨,王燕平*,林丽开,商洪才*,王永炎. 中药注射剂上市后整体评价的思路与关键[J]. 中国中药杂志,2017,42(16):3229-3232.................................46

[14]陈诗琪,杨欣宇,唐潇旖,李敏,刘硕,梁婧,张晓雨,商洪才*. 喘可治注射液治疗慢性阻塞性肺疾病急性加重期的系统评价[J].中国中药杂志,2017,42(14):2789-2795. ..................................................................................47

[15]曾宪涛,崔一民,冯佳佳,韩晟,李智平,林丽开,马融,马小军,任学群,戎萍,商洪才,申长春,申昆玲,史录文,史楠楠,王晓玲,张伶俐,郑波,王永炎*. 制订/修订《超说明书用药循证评价》的基本方法与程序[J]. 中国研究型医院,2017,(05):35-39. .............................................................................................48

[16]史楠楠,申长春,曾宪涛,何立群,胡元会,姜良铎,李博,马融,戎萍,商洪才,史录文,王雪峰,王燕平,林丽开,王永炎*. 《中成药超说明书使用循证评价》技术操作规范[J]. 中国研究型医院,2017,4(04):56-61. ......................................49

[17]翟静波,李江,商洪才,王辉,代敏*,陈静*. 贝叶斯单病例随机对照试验简介[J]. 中国循证医学杂志,2017,17(07):848-851. ...............................................50

[18]张晓雨,李敏,邱瑞瑾,杨欣宇,刘硕,张琴,李承羽,陈诗琪,陈静,商洪才*. 系统评价方法在中成药上市后再研究评价中的应用误区及反思[J].中国中西医结合杂志,2017,37(08):996-999. .........................................................................51

[19]陈耀龙,张晓雨,商洪才*. 中医药领域的证据与推荐:理论、方法与实践[J]. 世界中医药,2017,12(06):1209-1213. ................................................................52

[20]胡晶,刘卫红,张会娜,李博,张晓雨,商洪才*. “病证结合”多主要终点评价法在中医药临床研究中的应用[J].世界中医药,2017,12(06):1214-1217. .....53

[21]李江,翟静波,商洪才,杨克虎,田金徽,陈静*,代敏*. 单病例随机对照试验的证据级别和报告规范[J]. 中国循证医学杂志,2017,17(05):612-615. .........54

[22]赵晨,刘智,商洪才*. 中医临床疗效评价差异化策略的提出——个体化研究方法学元素初探[J]. 世界中医药,2017,12(06):1221-1225. .............................55

[23]赵晨,商洪才,王燕平*. 民间中医特色诊疗技术防治慢性疾病的优势与评价思路[J].世界中医药,2017,12(06):1226-1229 .................................................56

[24]邱瑞瑾,张晓雨,商洪才*. 证候类中药新药临床疗效评价方法探索[J]. 世界中医药,2017,12(06):1230-1234........................................................................57

[25]靳英辉,魏洪悦,王云云,李紫梦,许良燕,韩蕙安,杨柳,商洪才*. 中医非药物治疗老年性痴呆的证据总结与评价[J]. 世界中医药,2017,12(06):1235-1243+1247..........................................................................58

[26]王家莹,王俊峰,商洪才*. Spin——中医药临床证据报告的新挑战[J]. 世界中医药,2017,12(06):1244-1247........................................................................59

[27]刘岩*,李新龙,商洪才,刘志顺,何丽云,刘保延. 针刺治疗功能性便秘研究中校正填补值的模式混合模型方法[J]. 世界中医药,2017,12(06):1258-1260+1267. .........................................................................60

[28]牟玮,翟静波,李杰,刘智,靳英辉,黄宇虹,商洪才*. 中医临床证据的转化策略——决策辅助工具的研制[J]. 世界中医药,2017,12(06):1261-1267. .........61

[29]李博,郭玉红,胡晶,冯硕,张会娜,商洪才*. 中医药治疗功能性胃肠疾病临床试验研究方案及病历设计思考[J].世界中医药,2017,12(06):1268-1273 ..62

[30]刘莹,商洪才*. 心血管中成药超说明书用药循证评价方法和程序的建立[J].世界中医药,2017,12(06):1253-1257. ...................................................................63

[31]张晓雨,商洪才*. 复方中药的国际化发展策略[J]. 世界中医药,2017,12(06):1279-1281. ...................................................................................64

[32]翟静波,李江,商洪才,王辉,代敏*,陈静*. N-of-1试验的经济学评价[J]. 中国循证医学杂志,2017,17(06):742-744. ...........................................................65

[33]宋霄杨,高玉婷,周奇,王小琴,王琪,陈耀龙*,商洪才*. 非经济利益冲突及其研究现状[J]. 中国循证医学杂志,2017,17(05):607-611. .............................66

[34]王辉，翟静波，陈静*，李江，商洪才*，单病例随机对照试验的设计和实施要点[J]. 中国循证医学杂志,2017,17(03):364-368. .........................................67

[35]李江,翟静波,商洪才*,陈静,石菊芳,杨克虎,田金徽,代敏*. 单病例随机对照试验的起源与发展[J]. 中国循证医学杂志,2017,17(02):235-238. ...........68

4.中药药理方向

[36]盛宁,何瑛琨,冯慧利,董云芳,樊惠,党惠子,任映,杨金铎,王蓬文*. 半夏泻心汤和鸟嘌呤核苷对APPswe/PS1dE9双转基因小鼠学习记忆的影响[J]. 北京中医药大学学报, 2017,40(07):558-563. .................................................................69

5.药物分析方向

[37]乌仁曹布道,聂波,图雅*， 黄花黄芩不同提取物的红外光谱研究. 中国民族民间医药, 2017,26(05):10-13................................................................................70

[38]苏都娜,策力木格,侯彦宏,图雅*,聂波*. HPLC法测定蒙药复方五味清浊散中鞣花酸含量[J]. 中国民族民间医药, 2017,26(03):40-42. ............................71

[39]策力木格,张小峰,苏都娜,聂波,侯彦宏,松林*,图雅*， 血清药物化学在中药领域的应用现状.中国药房 ，201728(07):978-981. .........................................72

[40]赵丹，聂波，宋昆, 陈虹，洪云鹤，吴文杰，张峰.离子色谱法测定不同产地葛根多糖中的单糖组成.分析实验室.2017,36(7):745-749. ...........................73

6肾脏病、内分泌、风湿免疫方向

[41]丁劲,张耀圣,商建伟*,李曰庆,马健雄,柴立民,李宪锐,韦翊,盛文. 益肾健脾方对少弱精子症小鼠模型精液质量和精子线粒体结构及功能的影响[J]. 世界中西医结合杂志, 2017,12(05):641-645. .............................................................74

[42杨颖溪,柴立民,晏军*,高伟华,吴甜甜,朱紫亨,余佳骏,徐昉. 补肾益肺消癥方对α-SMA及SP-C蛋白对肺纤维化大鼠病变肺组织分布及表达的影响[J]. 环球中医药, 2017,10(06):559-563. ......................................................................75

[43]梁彩星,刘伟敬,刘华锋*,刘玉宁*. 纠正线粒体功能障碍对急性肾损伤的治疗作用[J]. 中国中西医结合肾病杂志, 2017,18(05):468-470. ........................76

[44]李雪,韦翊,邓培颖,董玢,金秋硕,柴立民*. 补肾生血解毒方对免疫介导的再生障碍性贫血小鼠淋巴细胞分化及血液学参数的影响[J]. 北京中医药大学学报, 2017 (10):833-838. ...........................................................................................77